Liquefied embolic materials capable of sol-gel phase transition and their use
US6562362B1 · kind B1 · utility
28Cited by
2References
11Claims
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Key dates
| Filing date | Nov 7, 2000 |
| Grant date | May 13, 2003 |
| Priority date | — |
| Expiry date | Jan 13, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2430/36
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are liquefied embolic materials capable of sol-gel phase transition in response to in vivo conditions, including temperature, ionic strength, and pH, and their uses. The liquefied embolic materials are made of copolymers based on temperature-sensitive isopropylacrylamide and ionic strength- and/or pH-sensitive monomers. In addition to finding excellent applications in the embolotherapy, the embolic materials can be used as extracellular matrixes for cell culture and for drug-delivery systems for cancer therapy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.