Compositions and mehtods for determining interactions of mitochondrial components, and for identifying agents that alter such interactions
US6562563B1 · kind B1 · utility
5Cited by
9References
28Claims
0Family size
Assignee
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Key dates
| Filing date | Nov 3, 1999 |
| Grant date | May 13, 2003 |
| Priority date | — |
| Expiry date | Nov 3, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/60
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Compositions and methods are provided for identifying agents that alter mitochondrial membrane permeability transition. The screening methods generally detect agents that alter the interaction between the mitochondrial adenine nucleotide translocator and cyclophilin D. Such agents may be used, for example, in the treatment of a variety of conditions associated with altered mitochondrial function.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.