Methods of synthesizing sultams and anti-viral compositions
US6562850B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 15, 1999 |
| Grant date | May 13, 2003 |
| Priority date | — |
| Expiry date | Jul 15, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D275/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to a new class of compounds herein identified generally as “sultams”, which may be represented by the following formula V, in FIG. 1, in which numbering of the atoms is started with the sulfur atom of the isothiazole. Two of the rings (rings A and C) are aromatic, and the third is a heterocyclic ring (ring B), a cyclic sulfonamide. Of particular importance are the enantiomerically pure sultams since they are especially potent HIV-1 inhibitors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.