4-phenyltetrahydrochinoline utilized as an inhibitor of the cholesterol ester transfer protein

US6562976B2 · kind B2 · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Gunter Schmidt · Houghton, US
• Jurgen Stoltefuss · Haan, DE
• Michael Logers · Wuppertal, DE
• Arndt Brandes · Wuppertal, DE
• Carsten Schmeck · Wuppertal, DE
• Klaus-Dieter Bremm · Recklinghausen, DE
• Hilmar Bischoff · Wuppertal, DE
• Delf Schmidt · Wuppertal, DE

Key dates

• Filing date: Apr 15, 2002
• Grant date: May 13, 2003
• Expiry date: Apr 15, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/06
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The tetrahydroquinolines can be prepared by condensing appropriately substituted tetrahydroquinoline aldehydes with suitable substances and subsequently varying the substituents present by customary methods. The tetrahydroquinolines are suitable as active compounds in medicaments, in particular in medicaments. for the treatment of arteriosclerosis and dyslipidaemias.