Identification of neoplasms by detection of genetic insertions and deletions
US6566053B1 · kind B1 · utility
1Cited by
5References
39Claims
0Family size
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Key dates
| Filing date | Dec 27, 1995 |
| Grant date | May 20, 2003 |
| Priority date | — |
| Expiry date | Dec 27, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/156
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The detection of insertions and/or deletions in reiterated nucleotide sequences in tissues provides an identification of neoplastic changes that are associated with malignancy. The mutations are preferably detected by PCR based amplification of target sequences using selected primers, followed by standard analytic procedures. The detection of these mutations is useful as a diagnostic tool for cancer development and has direct application for cancer prognosis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.