Aquaporin-8 variant
US6566066B1 · kind B1 · utility
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13Claims
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Assignee
Inventors
Key dates
| Filing date | Jul 6, 2000 |
| Grant date | May 20, 2003 |
| Priority date | — |
| Expiry date | Jul 6, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K48/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides a mammalian cDNA which encodes a mammalian AQP8V. It also provides for the use of the cDNA, fragments, complements, and variants thereof and of the encoded protein, portions thereof and antibodies thereto for diagnosis and treatment of pancreatic disorders, particularly type I diabetes. The invention additionally provides expression vectors and host cells for the production of the protein and a transgenic model system.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.