Syndecan-4 binding protein (S4BP) and uses thereof
US6566489B1 · kind B1 · utility
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25Claims
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Assignee
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Key dates
| Filing date | Mar 15, 2000 |
| Grant date | May 20, 2003 |
| Priority date | — |
| Expiry date | Mar 15, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K48/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a gene encoding a novel protein, syndecan-4 binding protein (S4BP), which binds to syndecan-4. S4BP polypeptides play a role in cell matrix interactions. Described herein are isolated and antisense nucleic acids molecules, recombinant expression vectors, host cells and non-human transgenic animals containing an insertion or a disruption of the S4BP gene. Diagnostic, screening and therapeutic methods utilizing the compositions of the invention are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.