Oligonucleotide sequences complementary to thioredoxin or thioredoxin reductase genes and methods of using same to modulate cell growth
US6566514B1 · kind B1 · utility
13Cited by
14References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 18, 2000 |
| Grant date | May 20, 2003 |
| Priority date | — |
| Expiry date | Oct 18, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/315
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to oligonucleotides complementary to the thioredoxin and thioredoxin reductase genes which modulate tumor cell growth in mammals. This invention is also related to methods of using such compounds in inhibiting the growth of tumor cells in mammals. This invention also relates to pharmaceutical compositions comprising a pharmaceutically acceptable excipient and an effective amount of a compound of this invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.