Patent · US Expired

Transgenic non-human mammals with an oncogenic mutant of Raf-1 gene

US6566581B1 · kind B1 · utility

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7Claims
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Inventor

Key dates

Filing dateJul 17, 2000
Grant dateMay 20, 2003
Priority date
Expiry dateJul 17, 2020

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2830/008
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The invention relates to a transgenic non-human mammal whose cells express a constitutively active oncogenic mutant of the kinase-domain of the Raf-1 gene or a protein coded by a corresponding normal allele or derivative of the A, B or c-Raf-1 gene.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.