Methods for multiple direct label probe detection of multiple chromosomes or regions thereof by in situ hybridization
US6569626B2 · kind B2 · utility
24Cited by
12References
16Claims
0Family size
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Key dates
| Filing date | Jun 21, 2001 |
| Grant date | May 27, 2003 |
| Priority date | — |
| Expiry date | Jun 21, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6816
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Direct label probe compositions which stain DNA of a preselected single chromosome or region of a chromosome of a multi-chromosomal genome are provided that comprise mixed DNA segments which are covalently bound to fluorophore groups through linking groups. The mixed DNA segments are derived from the DNA present in the preselected chromosome or chromosome region. These probe compositions can be used concurrently or sequentially with other probe compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.