Patent · US Expired

Method for assaying human thymidylate synthase and assay kit

US6569634B1 · kind B1 · utility

3Cited by
1References
8Claims
0Family size

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Key dates

Filing dateMay 1, 2000
Grant dateMay 27, 2003
Priority date
Expiry dateMay 1, 2020

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2333/91011
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

This invention relates to a method for immunologically measuring human thymidylate synthase with an anti-human thymidylate synthase antibody, wherein as the antibody, at least an anti-human thymidylate synthase polyclonal antibody immobilized on an insoluble matrix is used; a method for evaluating sensitivity of cancer cells to a fluoropyrimidine antitumor drug from the results of the measurement by the measuring method; and a human thymidylate synthase measuring kit comprising an insoluble matrix with at least one anti-human thymidylate synthase polyclonal antibody immobilized thereon. By a simple immunological measuring method, human TS in a sample can be measured with high sensitivity.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.