Recombinant &agr;-L-iduronidase, methods for producing and purifying the same and methods for treating diseases caused by deficiencies thereof
US6569661B1 · kind B1 · utility
40Cited by
5References
10Claims
0Family size
Assignee
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Key dates
| Filing date | Nov 9, 2000 |
| Grant date | May 27, 2003 |
| Priority date | — |
| Expiry date | Apr 21, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K48/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a recombinant human &agr;-L-iduronidase and biologically active fragments and mutants thereof, large scale methods to produce and purify commercial grade recombinant human &agr;-L-iduronidase enzyme as well as methods to treat certain genetic disorders including &agr;-L-iduronidase deficiency and mucopolysaccharidosis I (MPS 1).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.