Inhibitor of programmed cell death
US6570002B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 24, 2000 |
| Grant date | May 27, 2003 |
| Priority date | — |
| Expiry date | Feb 24, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K48/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a human apoptosis regulator protein (Aven) and polynucleotides which identify and encode Aven. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding Aven, and a method for producing Aven. The invention also provides for agonists, antibodies, or antagonists specifically binding Aven, and their use, in the prevention and treatment of diseases associated with expression of Aven. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding Aven for the treatment of diseases associated with the expression of Aven. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding Aven.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.