Use of 1-(aminoalkyl)-3-quinoxaline-2-on derivatives for the preparation of compounds having an antioxidant action

US6573265B2 · kind B2 · utility

Assignee

• Phafag Aktiengesellschaft · LI

Inventors

• Klaus Ehrenberger · Wien, AT
• Dominik Felix · Zürich, CH
• Peter König · Feldkirch, AT
• Burkhard Poeggeler · Oettingen, DE

Key dates

• Filing date: Dec 18, 2000
• Grant date: Jun 3, 2003
• Expiry date: Dec 18, 2020

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P39/06
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to the use of 1-(aminoalkyl)-3-quinoxaline-2-one derivatives, especially 1-diethylaminoethyl-3-quinoxaline-2-one derivatives of the formula (I), where R 3 is hydroxy, methoxy, ethoxy or hydrogen, or pharmaceutically compatible salts thereof, for the preparation of compounds having an antioxidant action and used for preventing or treating diseases caused by free radicals of the cellular oxygen metabolism, stimulating nerve cell growth, antagonizing glutamate receptors and/or stimulating the growth notably of glutamergic nerve cells.