Patent · US Expired

Naphthalene derivatives, their production and use

US6573289B1 · kind B1 · utility

12Cited by
2References
35Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 18, 2000
Grant dateJun 3, 2003
Priority date
Expiry dateOct 18, 2020

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D401/06
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A composition containing a compound of the formula: wherein A is a nitrogen-containing heterocyclic group which may be substituted, R1 is a hydrogen atom, hydrocarbon group which may be substituted, or monocyclic aromatic heterocyclic group which may be substituted, R2 is a hydrogen atom or a lower alkyl group which may be substituted, R3, R4, R5, R6, R7, R8 and R9 are independently a hydrogen atom, a hydrocarbon group which may be substituted, a hydroxy group which may be substituted, a thiol group which may be substituted, an amino group which may be substituted, an acyl group or a halogen atom, a salt thereof or a prodrug thereof has steroid C17,20-lyase inhibitory activity, and is useful for preventing and treating for example, primary cancer of malignant tumor, its metastasis and recurrence thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.