Self-compensating radiation sensor with wide dynamic range
US6573991B1 · kind B1 · utility
Inventors
Key dates
| Filing date | Apr 26, 2000 |
| Grant date | Jun 3, 2003 |
| Priority date | — |
| Expiry date | Apr 26, 2020 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2015/0294
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A radiation sensing method and device that is used to measure physical properties of materials over a wide dynamic range. The sensor (20) comprises multiple radiation sources and multiple detectors at multiple separation distances. The detected signals from the different sources are separated and then combined mathematically in a manner such that the combination is self-compensated for both component drift and changes in radiation coupling efficiency between the source or detector and the material of interest. In a preferred embodiment, the biomass in a liquid cell culture (54) is measured with high accuracy over a wide dynamic range using optical wavelength radiation. The measurement can be made with the sensor external to the liquid culture container in a manner that is compensated for the thickness of the container window (50).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.