Method for displacement chromatography
US6576134B1 · kind B1 · utility
Inventor
Key dates
| Filing date | Apr 19, 2001 |
| Grant date | Jun 10, 2003 |
| Priority date | — |
| Expiry date | Apr 19, 2021 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N30/02
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method of sample displacement chromatography separation which comprises applying a multicomponent sample to one end of a chromatography bed comprising stationary phase material having affinity for components of the sample, causing components of the sample to become distributed along the chromatography bed by passage over the bed of a non-eluting mobile solvent phase, and recovering a desired component of the sample from at lest a portion of the chromatography bed, in which the sample components are applied to the chromatography bed in a non-homogeneous manner such that the concentration of at least one component with relatively low affinity for the stationary phase material is enhanced during an earlier part of sample application and/or the concentration of at least one component with relatively high affinity for the stationary phase material is enhanced during a later part of sample application.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.