Peroxidase-activating oral compositions
US6576227B1 · kind B1 · utility
Assignee
Inventor
Key dates
| Filing date | Jan 26, 1999 |
| Grant date | Jun 10, 2003 |
| Priority date | — |
| Expiry date | Jan 26, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2800/412
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A peroxidase-activating oral care composition, in accordance with an embodiment of the invention, includes a non-enzymatic, water-soluble hydrogen peroxide precursor and a pH-adjusting agent capable of producing a selected pH in an aqueous solution. The composition facilitates the rapid release of hydrogen peroxide and results in the activation of a peroxidase enzyme in an oral cavity. A process for manufacturing the oral care composition including obtaining the precursor, dispersing it in a non-hygroscopic material so as to coat or encapsulate it, obtaining and associating the coated or encapsulated particles with a pH-adjusting agent, and formulating the particles into an oral care composition is provided in another embodiment. In addition, a method for activating a peroxidase system in an oral cavity of an animal, including selecting a non-enzymatic water soluble hydrogen peroxide precursor, mixing the precursor with a pH-adjusting agent, and administering the precursor and pH-adjusting agent in a suitable formulation to the oral cavity, is provided in a further embodiment of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.