Tumoricidal T lymphocytes

US6576466B2 · kind B2 · utility

Assignee

• Albert Winfried · DE

Inventors

• Herbert Jungfer · Starnberg, DE
• Heinrich Barchet · Deggendorf, DE
• Winfred Albert · Eberfing, DE
• Ulrich Weidle · Hersbruck, DE

Key dates

• Filing date: Dec 4, 1995
• Grant date: Jun 10, 2003
• Expiry date: Dec 4, 2015

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K2239/59
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention concerns a mammalian cell line which when co-cultured with lymphocytes during which allogenic stimulation is avoided activates lymphocytes fo form tumoricidal cells, a process for the production of tumoricidal T lymphocytes by co-culturing lymphocytes with this cell line, the tumoricidal T lymphocytes obtained by means of this process and the use of the cells according to the present invention for the production of a therapeutic agent which can be used in tumour therapy.