3-aryl-succinamido-hydroxamic acids, methods for producing said acids and medicaments containing the same

US6576628B1 · kind B1 · utility

Assignee

• Roche Diagnostics GMBH · DE

Inventors

• Frank Grams · Mannheim, DE
• Gerd Zimmermann · Eckental, DE
• Hans-Willi Krell · Penzberg, DE
• Ernesto Menta · Parma, IT
• Herbert Leinert · Heppenheim, DE

Key dates

• Filing date: Jul 6, 2000
• Grant date: Jun 10, 2003
• Expiry date: Jul 6, 2020

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to inhibitors of matrix metalloproteases, more specifically a 3-aryl-succinamido-hydroxamic acid of formula (I) and its salt, ester and derivative thereof, along with methods of producing a compound of formula (I) and pharmaceutical compositions thereof.