Patent · US Expired

&bgr;-alanine derivatives

US6576637B1 · kind B1 · utility

2Cited by

0References

10Claims

0Family size

Assignee

Merck Patent GmbH · DE

Inventors

Gunter Holzemann · Seeheim-Jugenheim, DE
Simon Goodmann · Darmstadt, DE
Alfred Jonczyk · Darmstadt, DE
Wolfgang Stahle · Ingelheim am Rhein, DE

Key dates

Filing date	Aug 20, 2001
Grant date	Jun 10, 2003
Priority date	—
Expiry date	Aug 20, 2021

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D239/42
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to &bgr;-alanine derivatives of formula (I), wherein Q1, Q2, Q3, Q4, R1, R2, R3, R4, R5, R6 and n have the meaning as disclosed in the disclosure, and to their physiologically acceptable salts or solvates. Said substances are integrin inhibitors and can be used in the treatment of thrombosis, heart infarct, coronary heart diseases, arteriosclerosis, inflammations, tumors, osteoporosis, infections and restenosis after angioplasty or in pathological processes induced or propagated by angiogenesis.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.