Compositions and uses of dictyostatin compounds
US6576658B2 · kind B2 · utility
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2Claims
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Key dates
| Filing date | Feb 26, 2001 |
| Grant date | Jun 10, 2003 |
| Priority date | — |
| Expiry date | Feb 26, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/43595
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Dictyostatin-1 has been found to stabilize microtubules and prohibit their depolymerization to free tubulin. Because of these activities, the dictyostatin compounds can be used in the treatment of a number of diseases in which aberrant cellular proliferation occurs such as drug-sensitive and drug-resistant cancers, autoimmune disorders, and inflammatory diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.