Ocular iontophoretic device and method for inhibiting vascular endothelial growth factor (VEGF) using the same
US6579276B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 22, 2001 |
| Grant date | Jun 17, 2003 |
| Priority date | — |
| Expiry date | Jan 22, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61F9/0008
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
An ocular iontophoretic device for delivering an aptamer to an affected area of a living being's eye for inhibiting VEGF function therein, the device comprising an active electrode assembly associated with a matrix and/or reservoir, wherein the matrix and/or reservoir includes an aptamer capable of inhibiting VEGF function.A method for treating an affected area of a living being's eye, comprising the steps of: associating an aptamer with an ocular iontophoretic device; positioning at least a portion of an ocular iontophoretic device on the eye of the living being; and iontophoretically delivering the aptamer to an affected area of the living being's eye.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.