Sustained release and long residing ophthalmic formulation and the process of preparing the same

US6579519B2 · kind B2 · utility

Assignee

• Registrar, University of Delhi · IN

Inventors

• Amarnath Maitra · Chicago, US
• Ajay Gupta · Savanuru, IN
• Dipak Majumdar · New Delhi, IN
• Sumit MADAN · New Delhi, IN

Key dates

• Filing date: Sep 18, 2001
• Grant date: Jun 17, 2003
• Expiry date: Sep 18, 2021

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K47/34
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to sustained release and long residing opthalmic formulation having thermosensitivity, mucoadhesiveness, hydro gel properties and small particle size. The said formulation comprises micelle solution of random block co-polymer having a hydrophobic component and a hydrophillic component of general formula —(X+Y+Z-)m, and at least one hydrophobic drug with the block co-polymer solution. The invention also provides a process of preparing said formulation.