Method for producing fibronectin and fibrinogen compositions using a polyalkylene glycol and glycine or &bgr;-alanine
US6579537B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 10, 2000 |
| Grant date | Jun 17, 2003 |
| Priority date | — |
| Expiry date | Feb 10, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/78
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method of producing a pharmaceutical preparation comprising fibronectin and fibrinogen is disclosed. The method involves admixing into a starting solution of fibrinogen and fibronectin, in a single step, a precipitating composition comprising a polyalkylene glycol and at least one of glycine and &bgr;-alanine which forms a precipitate. Next, the precipitate is collected and a pharmaceutical preparation is prepared from the precipitate. The pharmaceutical preparation has a fibronectin:fibrinogen ratio from about 0.02 to about 0.2.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.