Patent · US Expired

Method for producing fibronectin and fibrinogen compositions using a polyalkylene glycol and glycine or &bgr;-alanine

US6579537B2 · kind B2 · utility

15Cited by
15References
18Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 10, 2000
Grant dateJun 17, 2003
Priority date
Expiry dateFeb 10, 2020

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K14/78
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

A method of producing a pharmaceutical preparation comprising fibronectin and fibrinogen is disclosed. The method involves admixing into a starting solution of fibrinogen and fibronectin, in a single step, a precipitating composition comprising a polyalkylene glycol and at least one of glycine and &bgr;-alanine which forms a precipitate. Next, the precipitate is collected and a pharmaceutical preparation is prepared from the precipitate. The pharmaceutical preparation has a fibronectin:fibrinogen ratio from about 0.02 to about 0.2.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.