Blood analyte monitoring through subcutaneous measurement
US6579690B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 24, 2000 |
| Grant date | Jun 17, 2003 |
| Priority date | — |
| Expiry date | Jul 24, 2020 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/817
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
One embodiment of the invention is a method for obtaining an estimate of an analyte concentration in a first fluid. First, measurements of an analyte concentration in a second fluid are obtained using a sensing device. An analyte concentration estimate in the first fluid is determined from these measurements by minimizing the relation: f[b]=x2[b]+&lgr;&PSgr;[b], where b is a vector representing analyte concentration in the first body fluid, X2[b] is a function representing a fit between the estimates and the measurements, &lgr; is a weighting function, and &PSgr;[b] is a function indicating smoothness of the analyte concentration estimates in the first fluid. Another embodiment includes a sensing device for obtaining the measurements of an analyte concentration in the first fluid and a processor configured and arranged to determine the analyte concentration in the first body fluid according to this method. This method and device can be used, for example, to determine blood glucose concentration from measurements of the glucose concentration in subcutaneous tissue. These measurements may be made using in vitro or in vivo samples. In some instances, a subcutaneously implanted sensing…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.