Antibiotic peptides from bovine milk

US6579849B2 · kind B2 · utility

Assignee

• Haemopep Pharma GmbH · DE

Inventors

• Wolf-Georg Forssmann · Hannover, DE
• Hans-Dieter Zucht · Hannover, DE
• Manfred Raida · Hannover, DE
• Knut Adermann · Hannover, DE
• Hans-Jurgen Magert · Hannover, DE

Key dates

• Filing date: Sep 24, 1998
• Grant date: Jun 17, 2003
• Expiry date: Sep 24, 2018

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A peptide having the amino acid sequenceH2N—X1—R—X3—X2—COOH  (formula I) whereinX1 is either zero orX1 and/or X2 are a residue representing at least five amino acid residues (symbolized in the one letter amino acid code), preferably naturally occurring amino acids,with the proviso thatX1 and/or X2 contain at least one basic amino acid residue immediately followed by a hydrophobic amino acid residue andX1 and/or X2 contain at least one glutamine residue.