3 (5)-heteroaryl substituted pyrazoles as p38 kinase inhibitors

US6579873B2 · kind B2 · utility

Assignee

• Pharmacia Corporation · SE

Inventors

• Ashok Anantanarayan · Hainesville, US
• Michael Clare · Skokie, US
• Lifeng Geng · Skokie, US
• Gunnar J. Hanson · Cambridge, US
• Richard A. Partis · Evanston, US
• Michael A. Stealey · Libertyville, US
• Richard M. Weier · Lake Bluff, US

Key dates

• Filing date: Dec 18, 2001
• Grant date: Jun 17, 2003
• Expiry date: Dec 18, 2021

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D401/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A class of pyrazole derivatives is described for use in treating p38 kinase mediated disorders. Compounds of particular interest are defined by Formula I wherein R1, R2, Ar1 and HetAr2 are as described in the specification.