Methods to identify compounds affecting mitochondria
US6586241B1 · kind B1 · utility
0Cited by
5References
3Claims
0Family size
Assignee
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Key dates
| Filing date | Oct 6, 2000 |
| Grant date | Jul 1, 2003 |
| Priority date | — |
| Expiry date | Oct 6, 2020 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/5079
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to methods for identifying a compound capable of modulating mitochondrial function, comprising contacting a eukaryotic cell with one or more candidate compounds, and detecting a change in the mitochondrial redox state of the cell. The methods further relates to such methods wherein endogenous fluorescence of the cell mitochondria is indicative of a change of redox state.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.