Patent · US Expired

Method for the preparation of tetrahydrobenzothiepines

US6586434B2 · kind B2 · utility

6Cited by
50References
32Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 8, 2001
Grant dateJul 1, 2003
Priority date
Expiry dateMar 8, 2021

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D487/08
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Among its several embodiments, the present invention provides an improved process for the preparation of tetrahydrobenzothiepine-1,1-dioxide compounds; the provision of a process for preparing a diastereomeric mixture of tetrahydrobenzothiepine-1,1-dioxide compounds from a single diastereomer of such compounds; the provision of a process for the preparation of 3-bromo-2-substituted propionaldehyde compounds; and the provision of a process for the preparation of 3-thio-2-substituted propionaldehyde compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.