Benzimidazolone derivatives displaying affinity at the serotonin and dopamine receptors
US6586435B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 21, 2001 |
| Grant date | Jul 1, 2003 |
| Priority date | — |
| Expiry date | Aug 21, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compound of formula (I) wherein:R1 is hydrogen or C1-C6-alkyl optionally substituted by C3-C6-cycloylalkyl;R2 and R3 together with the nitrogen form a saturated or unsaturated 5- or 6-membered heterocyclic ring optionally containing nitrogen or oxygen as an additional heteroatom, wherein the heterocyclic ring thereof is substituted by a group selected from phenyl, benzyl, and diphenylmethyl, each optionally mono- or di-substituted by one or two groups selected from CF3, C1-C4-alkyl, C1-C4-alkoxy, phenyl, benzyl, halogen, and OH, orR2 and R3 together with the nitrogen form a saturated or unsaturated 5- or 6-membered heterocyclic ring optionally containing nitrogen or oxygen as an additional heteroatom, the heterocyclic ring thereof linked via a single bond, a methylene-bridge, or spiro-connected to another saturated or unsaturated heterocyclic group containing one or two heteroatoms selected from oxygen and nitrogen, the heterocyclic group being optionally mono- or di-substituted by a group selected from CF3, C1-C4-alkyl, C1-C4-alkoxy, phenyl, benzyl, halogen, ═O, and OH, orR2 and R3 together with the nitrogen form a saturated or unsaturated bi- or tricyclic heterocyclic ring s…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.