Nicotine-containing, controlled release composition and method
US6586449B1 · kind B1 · utility
Assignee
Inventor
Key dates
| Filing date | May 28, 2002 |
| Grant date | Jul 1, 2003 |
| Priority date | — |
| Expiry date | May 28, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P25/34
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A nicotine product having a nicotine release rate of not less than 70% over a 10 minute period as well as a process to produce such product Such product is produced by a process comprising the steps of(a) preparing an aqueous solution of an organic polyol;(b) mixing said aqueous solution of the organic polyol with a cation exchange resin selected from the group consisting of (i)—a methacrylic, weakly acidic type of resin containing carboxylic functional groups (ii)—polystyrene, strongly acidic type of resin containing sulfonic functional groups and (iii)—polystyrene, intermediate acidic type of resin containing phosphonic functional groups thereby forming a cation exchange resin mixture having some of its ion exchange sites partially blocked with said polyol;(c) admixing with said mixture of step (b) an aqueous solution of nicotine to form a nicotine-coated cation exchange resin admixture; and(d) removing water from said admixture. The nicotine composition having a nicotine release rate of not less than 70% over a 10 minute period results.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.