Cellular targeting poly(ethylene glycol)-grafted polymeric gene carrier
US6586524B2 · kind B2 · utility
126Cited by
0References
29Claims
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Assignee
Inventor
Key dates
| Filing date | Jul 19, 2001 |
| Grant date | Jul 1, 2003 |
| Priority date | — |
| Expiry date | Jul 19, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K48/0041
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to cationic polymeric conjugates and methods of preparing and using them as gene carriers. The cationic polymeric conjugates comprise a poly(ethylene glycol) (PEG) grafted cationic polymer and a targeting moiety(TM), wherein 0.1 to 10 mole percent of the cationic groups of the cationic polymer are substituted with PEG-TM.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.