Atmospheric pressure ionization ion mobility spectrometry
US6586732B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 20, 2001 |
| Grant date | Jul 1, 2003 |
| Priority date | — |
| Expiry date | Oct 6, 2021 |
Classification
- Technology area (CPC H)Electricity
- CPC primaryH01J49/165
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A high voltage ion propulsion field is applied across the length of an ion mobility spectrometer that is divided by a barrier wall into a desolvation region and a drift tube. A plume of ions and solvent is electrosprayed into the desolvation region, and ions are propelled from the desolvation region through the drift tube to an ion target. Drift gas flows through the drift tube in the opposite direction to oppose the ion flow. A portal in the barrier wall permits ions to move from the desolvation region into the drift tube, and restricts flow of drift gas from the drift tube into the desolvation region. The resulting drift gas velocity increase effects desolvation without requiring elevated temperature or decreased pressure. An ion gate is located near the portal and an aperture grid is located near the ion target. The drift gas flow rate is varied to change the ionization spectra to alter selectivity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.