Tablets quickly disintegrating in the oral cavity and process for producing the same
US6589554B1 · kind B1 · utility
Assignees
Inventors
Key dates
| Filing date | Sep 14, 2000 |
| Grant date | Jul 8, 2003 |
| Priority date | — |
| Expiry date | Sep 14, 2020 |
Classification
- Technology area (CPC H)Electricity
- CPC primaryH04L69/329
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a quick disintegrating tablet in buccal cavity, comprising: a mixture, comprising a drug, a sugar (A), and an amorphous sugar (B), and after it is forming a tablet, it is humidified and dried. In particularly, the present invention relates to a quick disintegrating tablet in buccal cavity comprising: a mixture; comprising a drug, a sugar (A), and an amorphous sugar (B) which an amorphous-forming sugar in crystalline state is dissolved in a medicinally permitted solvent, the amorphous sugar is obtained from this solution by removing the solvent, and after it is forming a tablet, and it is humidified and dried.The tablet in the present invention is to provide stability against moisture at preserved, because the amorphous sugar changed to the crystalline state in a nonreversible reaction after it is humidified and dried in a manufacturing process. The tablet in the present invention is to further provide a design for the pharmaceutical preparation with respect to the stability of a drug, because the tablet is manufactured by one kind of a sugar and an amorphous sugar. Furthermore, the tablet in the present invention is to provide a production process b…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.