Methods for identifying protein-protein interactions by selective transduction
US6589730B1 · kind B1 · utility
4Cited by
3References
25Claims
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Key dates
| Filing date | Nov 17, 1998 |
| Grant date | Jul 8, 2003 |
| Priority date | — |
| Expiry date | Nov 17, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2799/021
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for identifying specific protein-protein (i.e., ligand/anti-ligand) interactions that internalize and are detected by transgene expression. A ligand displaying genetic package that carries a reporter or selectable marker and presents a ligand or putative ligand on its surface is utilized to screen cells displaying known or putative anti-ligands for the ability to successfully internalize the ligand displaying genetic package.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.