Cyclic compounds and their use as precursors of fragrant alcohols

US6589921B2 · kind B2 · utility

Assignee

• FIRMENICH SA · CH

Inventors

• Andreas Herrmann · Stuttgart, DE
• Jean-Yves Billard De Saint-Laumer · Beaumont, FR
• Otto Gräther · Carouge, CH

Key dates

• Filing date: Apr 2, 2002
• Grant date: Jul 8, 2003
• Expiry date: Apr 2, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C69/757
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of the formula: in which the dotted lines indicate the position of single or double bonds, R1 represents a radical belonging to a fragrant alcohol of the formula R1OH, X represents a nucleophilic group selected from the group consisting of —OH, ═O, —NH2 or —NHR3, R3 representing a C1 to C6 straight-chain or branched hydrocarbon radical, saturated or unsaturated, or an aliphatic or aromatic ring having 5 or 6 carbon atoms, m and n define whole numbers within the range 0 to 2 such that the sum m+n is equal to 1 or 2, p defines a whole number with a value of 0 or 1, each of the symbols R2, R4, R5, R6, R7, taken independently, represents a hydrogen atom, a C1 to C4 straight-chain or branched hydrocarbon radical, saturated or unsaturated optionally substituted, and, taken two by two, they can form aromatic or aliphatic monocyclic, bicyclic or tricyclic substances with the carbon atoms to which they are bound. Such compounds are capable of releasing a fragrant alcohol of the formula R1OH upon hydrolysis of the ester bond.