Antibacterial aqueous ophthalmic formulations containing ofloxacin and use of chitosan for solubilizing ofloxacin suspended in an aqueous media
US6589999B2 · kind B2 · utility
3Cited by
1References
17Claims
0Family size
Assignee
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Key dates
| Filing date | May 17, 2001 |
| Grant date | Jul 8, 2003 |
| Priority date | — |
| Expiry date | May 17, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The aqueous ophthalmic formulation for the treatment and prevention of infections contains ofloxacin as active ingredient and a chitosan having a weight average molecular weight of 500,000-5,000,000 Daltons and a deacetylation degree of 30-90% as solubilizing agent of ofloxacin. Chitosan having a deacetylation degree of 30-90% may be also used for solubilizing ofloxacin suspended in an aqueous media having a substantially neutral pH in any other applications.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.