Engineered muscle

US6592623B1 · kind B1 · utility

Assignee

• VIRGINIA COMMONWEALTH UNIVERSITY INTELLECTUAL PROPERTY FOUNDATION · US

Inventors

• Gary Bowlin · Mechanicsville, US
• Gary Wnek · Cleveland, US
• David Simpson · Mechanicsville, US
• Louis Terracio · New York, US

Key dates

• Filing date: Aug 31, 1999
• Grant date: Jul 15, 2003
• Expiry date: Aug 31, 2019

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61L2430/30
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

A muscle implant includes an extracellular matrix, tendon and muscle cells. The extracellular matrix is made of a matrix of electrospun polymer fibers. The tendon is made of extruded collagen fibers and the muscle cells are disposed on the extracellular matrix in such a manner that the combination of components will functionally and structurally act as normal muscle tissue. Cardiac and smooth muscles may be similarly formed without tendons but including the extracellular matrix and muscle cells.