Method of using alpha-keto enamine derivatives as ingredients and products incorporating same

US6592884B2 · kind B2 · utility

Assignee

• NESTEC S.A. · CH

Inventors

• Thomas Hofmann · Doylestown, US
• Harald Ottinger · Munich, DE
• Oliver Frank · Allershausen, DE
• Tomislav Soldo · Munich, DE
• Christoph Cerny · Winterthur, CH
• Fabien Robert · Gex, FR
• Imre Blank · Savigny, CH

Key dates

• Filing date: May 23, 2001
• Grant date: Jul 15, 2003
• Expiry date: May 23, 2021

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2601/16
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention concerns the food, cosmetic and pharmaceutical compositions including a compound of general formula: alone or in combination, as an ingredient for food, cosmetic, pharmaceutical, and perfume compositions, wherein R1 includes N-Pyrrolidinyl, N-Pyridinyl, N-(amino-diethyl), N-(2-carboxy-pyrrolidinyl), N-(2-Methoxycarbonyl-pyrrolidinyl), or a combination thereof; R2 includes hydrogen, methyl, or a combination thereof; X includes methylene, ethylidene, 1-Propylidene, oxy radical, or a combination thereof; and Y includes methylene, ethylidene, 1-propylidene, oxy radical, ethan-1,2-diyl, ethen-1,2-diyl, propan-1,2-diyl, ethan-1,2-oxy-1,2-yl, or a combination thereof. Food products containing such compositions, as well as methods of imparting a cooling effect on a consumer's skin, are also included.