Piperadinyl-substituted pyridylalkane, alkene and alkine carboxamides

US6593344B1 · kind B1 · utility

Assignee

• Klinge Pharma GmbH · DE

Inventors

• Elfi Biedermann · Vaterstetten, DE
• Max Hasmann · Schwanau, DE
• Roland Loser · Feldafing, DE
• Benno Rattel · Munich, DE
• Friedemann Reiter · Putzbrunn, DE
• Barbara Schein · Neufahrn, DE
• Klaus Seibel · Gräfelfing, DE
• Klaus Vogt · Munich, DE
• Katja Wosikowski · Poing, DE
• Isabel Schemainda · Munich, DE

Key dates

• Filing date: Jun 16, 2000
• Grant date: Jul 15, 2003
• Expiry date: Jun 16, 2020

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07F9/65583
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to new piperidinyl-substituted pyridyl carboxamides of the general formula (I), wherein the structure element E has meanings (E1) or (E2) and whereby the heterocyclic ring can optionally have a double bond. These substances have especially high cytostatic activities and pronounced immunosuppressive properties which make them suitable for therapeutic treatment in broad tumor spectrum.