Patent · US Expired

RXR modulators with improved pharmacologic profile

US6593493B1 · kind B1 · utility

7Cited by
51References
85Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 14, 2000
Grant dateJul 15, 2003
Priority date
Expiry dateMar 23, 2021

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D307/54
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention provides a novel class of RXR modulator compounds that exhibit an improved pharmacologic profile relative to the profile of previously studied RXR modulators, including those that share common structural features with the presently claimed modulators. The present invention also provides synthetic methods for preparing these compounds as well as pharmaceutical compositions incorporating these novel compounds and methods for the therapeutic use of such compounds and pharmaceutical compositions.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.