Quinoline derivatives useful for inhibiting farnesyl protein transferase
US6596735B1 · kind B1 · utility
12Cited by
3References
15Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Nov 28, 2000 |
| Grant date | Jul 22, 2003 |
| Priority date | — |
| Expiry date | Nov 28, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to compounds of the formula: and to pharmaceutically acceptable salts and solvates thereof wherein Y, R1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 have the meanings defined in the specification. The invention also relates to pharmaceutical compositions comprising said compounds and to the use of said compounds for inhibiting abnormal cell growth in mammals. The compounds of the above formula have activity as farnesyl protein transferase inhibitors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.