Antidiabetic 4-hydroxy-2-furoic acids
US6596760B1 · kind B1 · utility
4Cited by
2References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 18, 2002 |
| Grant date | Jul 22, 2003 |
| Priority date | — |
| Expiry date | Oct 18, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P17/16
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Substituted 4-hydroxy-2-furoic acids are obtained by the fermentation of an asterriquinone, which is a natural product having a 2,5-dioxy-3,6-bis(indolyl)quinone structure. The compounds modulate insulin receptor tyrosine kinase activity and may be useful in the treatment of diabetes and other diseases or conditions characterized by impaired endogenous insulin production or an impaired response to endogenous insulin.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.