Patent · US Expired

Process for the preparation of nefazodone hydrochloride

US6596866B2 · kind B2 · utility

0Cited by

3References

14Claims

0Family size

Assignee

Brantford Chemicals Inc. · CA

Inventors

K. S. Keshava Murthy · Brantford, CA
Bhaskar Reddy Guntoori · Brantford, CA
Daqing Che · Taizhou City, CN

Key dates

Filing date	Sep 17, 2001
Grant date	Jul 22, 2003
Priority date	—
Expiry date	Sep 29, 2021

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D249/12
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

A process for the preparation of Nefazodone hydrochloride comprising direct conversion of semicarbazide dihydrochloride 3 into Nefazodone hydrochloride which process involves a reaction of triethyl orthopropionate in the presence of trimethylsilylchloride and hydrochloric acid.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.