Patent · US Expired

Biphasic reaction vessel and methods of use

US6599754B2 · kind B2 · utility

4Cited by

8References

5Claims

0Family size

Assignee

University of Rochester · US

Inventors

Benjamin L. Miller · Penfield, US
Bryan Klekota · Del Mar, US

Key dates

Filing date	Apr 20, 2001
Grant date	Jul 29, 2003
Priority date	—
Expiry date	Jul 6, 2021

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10T436/255
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

A reaction vessel and method of identifying a ligand having affinity for a target molecule are disclosed. The reaction vessel includes a first member defining a first chamber, the first chamber including an organic solvent and a plurality of reactants which form a combinatorial library of products; a second member defining a second chamber, the second chamber including a target molecule and an aqueous solvent immiscible in the organic solvent; and a semipermeable membrane separating the contents of the first chamber from the contents of the second chamber, wherein said semipermeable membrane is permeable to one or more products of the combinatorial library of products.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.