Non-steroidal estrogen receptor ligands
US6599921B2 · kind B2 · utility
1Cited by
10References
22Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 21, 2001 |
| Grant date | Jul 29, 2003 |
| Priority date | — |
| Expiry date | Aug 21, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D311/80
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Novel non-steroidal estrogen receptor ligands and methods of synthesis are disclosed. The novel molecules are intended for use in therapeutic preparations for the treatment of estrogen receptor related disease states. The compounds specified are tetra-cyclic derivatives and have been shown to be antiproliferative against human estrogen-dependent cancer cells and to have good binding affinity for the estrogen receptor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.