PROCESS FOR THE PREPARATION OF N-(1,1-DIMETHYLETHYL)-4-[[5′-ETHOXY-4-CIS[2-(4-MORPHOLINO)ETHOXY]-2′-OXOSPIRO[CYCLOHEXAN-1,3′[H]INDOL]1′(2′-H)-YL]-SULFONYL]-3-METHOXYBENZAMIDE AND ITS SALTS
US6600039B1 · kind B1 · utility
1Cited by
2References
2Claims
0Family size
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Key dates
| Filing date | Apr 17, 2002 |
| Grant date | Jul 29, 2003 |
| Priority date | — |
| Expiry date | Apr 17, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P5/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to a process for the preparation of a compound of formula (I) and the salts thereof by reacting the compound of formula (II) with the compound of formula (III), which comprises carrying out the reaction in dimethyl sulfoxide, at a temperature between 10° C. and 40° C., preferably at room temperature and transforming the resulting base of formula (I), if desired, into its salt by a method known per se.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.