Patent · US Expired

Process for making amlodipine maleate

US6600047B2 · kind B2 · utility

16Cited by

12References

24Claims

0Family size

Assignee

Synthon B.V. · NL

Inventors

Franciscus B. G. Benneker · Nijmegen, NL
Pavel Slanina · Lelekovice, CZ
Frantisek Picha · Brno, CZ

Key dates

Filing date	Aug 27, 2001
Grant date	Jul 29, 2003
Priority date	—
Expiry date	Aug 27, 2021

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D211/90
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A process for making amlodipine maleate comprises reacting amlodipine or an acid addition salt thereof with maleic acid under an acidic environment to form an amlodipine maleate product. The process allows for the formation of amlodipine maleate substantially free from amlodipine aspartate.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.