Process for preparing 3-hydroxyesters from epoxide derivatives
US6600065B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 17, 2002 |
| Grant date | Jul 29, 2003 |
| Priority date | — |
| Expiry date | Oct 17, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C67/37
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Disclosed herein is a novel process for preparing 3-hydroxyesters, comprising: (a) reacting an epoxide derivative with carbon monoxide and alcohol in a solvent at a temperature of 30˜150° C. under a pressure of 50˜3000 psig by using a catalyst system consisting of a catalytic amount of a cobalt compound and optionally an effective amount of a promoter to produce a 3-hydroxyester or a derivative thereof; (b) separating the resulting product and the solvent from the cobalt compound and the promoter in a stripping column at a temperature of −30˜200° C. in an atmosphere of a stabilizing gas; and (c) recycling a part or all of the separated cobalt compound and promoter to the step (a) and repeating the steps (a) through (c).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.